Tumorigenicity is the tendency for cultured cells to give rise to either benign or malignant growing tumors when infected to in immunologically nonresponsive animals. Assessing and managing the tumorigenicity of all final products is essential in order to prevent ectopic tissue formation, tumor development or malignant transformation elicited by residual pluripotent stem cells after implantation (Kuroda T et al., Biol Pharm Bull. 2013;36(2):189-92.)
Texcell has developed a full range of in vivo assays to assess the tumorigenicity cells monitoring the development of possible tumors in immunosuppressed animals or in in vitro test systems.
Please visit vivo Science, a Texcell company, for more information or for additional tests.